{"version":"1.0","provider_name":"European Radiology","provider_url":"https:\/\/journals.myesr.org\/eur-radiol","title":"Reply to: A Comment on 'Apparent Diffusion Coefficient (ADC) in Distinguishing Haemangiomas from Malignant Vertebral Lesions in Whole-Body Diffusion-Weighted MRI' - European Radiology","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"6k4rJnZFMY\"><a href=\"https:\/\/journals.myesr.org\/eur-radiol\/opinions\/reply-distinguishing-haemangiomas\/\">Reply to: A Comment on &#8216;Apparent Diffusion Coefficient (ADC) in Distinguishing Haemangiomas from Malignant Vertebral Lesions in Whole-Body Diffusion-Weighted MRI&#8217;<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/journals.myesr.org\/eur-radiol\/opinions\/reply-distinguishing-haemangiomas\/embed\/#?secret=6k4rJnZFMY\" width=\"600\" height=\"338\" title=\"&#8220;Reply to: A Comment on &#8216;Apparent Diffusion Coefficient (ADC) in Distinguishing Haemangiomas from Malignant Vertebral Lesions in Whole-Body Diffusion-Weighted MRI&#8217;&#8221; &#8212; European Radiology\" data-secret=\"6k4rJnZFMY\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script type=\"text\/javascript\">\n\/* <![CDATA[ *\/\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/* ]]> *\/\n<\/script>\n","description":"Dear Dr Kuzan, We thank you for your letter. We agree that the phenotype of bone metastases can influence ADC. Our previously published work in this journal (1) demonstrated significant differences between tumour types and significantly lower ADC in sclerotic metastases compared to lytic metastases. We also agree that ADC in bone marrow is influenced [&hellip;]"}