{"id":143,"date":"2019-01-24T11:58:37","date_gmt":"2019-01-24T11:58:37","guid":{"rendered":"https:\/\/journals.myesr.org\/eur-radiol-exp\/2019\/01\/24\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/"},"modified":"2025-10-22T13:03:24","modified_gmt":"2025-10-22T12:03:24","slug":"rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer","status":"publish","type":"post","link":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/","title":{"rendered":"Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-844 alignleft\" src=\"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/Fig-2a-De-Cecco-et-al-Jan-2019.jpg\" alt=\"Fig 2a De Cecco et al Jan 2019\" width=\"394\" height=\"317\" \/>This prospective study was designed to examine the diagnostic performance of integrated positron emission tomography and dual-energy computed tomography imaging in determining the thoracic nodal status of patients with small-cell lung cancer or non-small-cell lung cancer. It also focused on the investigating the resulting impact on target volume delineation for radiation therapy planning.<\/p>\n<p><strong>Article<\/strong>: <a href=\"https:\/\/eurradiolexp.springeropen.com\/articles\/10.1186\/s41747-018-0047-4\" target=\"_blank\">Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer<\/a><\/p>\n<p><strong>Authors<\/strong>: Carlo N. De Cecco, Philip Burchett, Marly van Assen, James Ravenel, Samuel Lewis Cooper, Hong Li, Marques L. Bradshaw, William J. Rieter, U. Joseph Schoepf and Leonie Gordon<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This prospective study was designed to examine the diagnostic performance of integrated positron emission tomography and dual-energy computed tomography imaging in determining the thoracic nodal status of patients with small-cell lung cancer or non-small-cell lung cancer. It also focused on the investigating the resulting impact on target volume delineation for radiation therapy planning. Article: Rationale [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":27,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-143","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer - European Radiology Experimental<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer - European Radiology Experimental\" \/>\n<meta property=\"og:description\" content=\"This prospective study was designed to examine the diagnostic performance of integrated positron emission tomography and dual-energy computed tomography imaging in determining the thoracic nodal status of patients with small-cell lung cancer or non-small-cell lung cancer. It also focused on the investigating the resulting impact on target volume delineation for radiation therapy planning. Article: Rationale [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"European Radiology Experimental\" \/>\n<meta property=\"article:published_time\" content=\"2019-01-24T11:58:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-10-22T12:03:24+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/header-bg.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2048\" \/>\n\t<meta property=\"og:image:height\" content=\"1200\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"devsk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"devsk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/\",\"url\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/\",\"name\":\"Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer - European Radiology Experimental\",\"isPartOf\":{\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/header-bg.jpg\",\"datePublished\":\"2019-01-24T11:58:37+00:00\",\"dateModified\":\"2025-10-22T12:03:24+00:00\",\"author\":{\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/#\/schema\/person\/9e0037141ecf4639286bd117d53c7f8f\"},\"breadcrumb\":{\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#primaryimage\",\"url\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/header-bg.jpg\",\"contentUrl\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/header-bg.jpg\",\"width\":2048,\"height\":1200},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/#website\",\"url\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/\",\"name\":\"European Radiology Experimental\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/#\/schema\/person\/9e0037141ecf4639286bd117d53c7f8f\",\"name\":\"devsk\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/4ee8d4f6e30c151a9fa73266563f66052dc70da05f90a1df876c0269843f9ecb?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/4ee8d4f6e30c151a9fa73266563f66052dc70da05f90a1df876c0269843f9ecb?s=96&d=mm&r=g\",\"caption\":\"devsk\"},\"sameAs\":[\"https:\/\/journals.myesr.org\"],\"url\":\"https:\/\/journals.myesr.org\/eur-radiol-exp\/author\/devsk\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer - European Radiology Experimental","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/","og_locale":"en_GB","og_type":"article","og_title":"Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer - European Radiology Experimental","og_description":"This prospective study was designed to examine the diagnostic performance of integrated positron emission tomography and dual-energy computed tomography imaging in determining the thoracic nodal status of patients with small-cell lung cancer or non-small-cell lung cancer. It also focused on the investigating the resulting impact on target volume delineation for radiation therapy planning. Article: Rationale [&hellip;]","og_url":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/","og_site_name":"European Radiology Experimental","article_published_time":"2019-01-24T11:58:37+00:00","article_modified_time":"2025-10-22T12:03:24+00:00","og_image":[{"width":2048,"height":1200,"url":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/header-bg.jpg","type":"image\/jpeg"}],"author":"devsk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"devsk","Estimated reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/","url":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/","name":"Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer - European Radiology Experimental","isPartOf":{"@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/#website"},"primaryImageOfPage":{"@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#primaryimage"},"image":{"@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/header-bg.jpg","datePublished":"2019-01-24T11:58:37+00:00","dateModified":"2025-10-22T12:03:24+00:00","author":{"@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/#\/schema\/person\/9e0037141ecf4639286bd117d53c7f8f"},"breadcrumb":{"@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#primaryimage","url":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/header-bg.jpg","contentUrl":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-content\/uploads\/sites\/4\/2025\/10\/header-bg.jpg","width":2048,"height":1200},{"@type":"BreadcrumbList","@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/blog\/rationale-design-prospective-study-first-integrated-petdual-energy-ct-system-staging-image-based-radiation-therapy-planning-lung-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/journals.myesr.org\/eur-radiol-exp\/"},{"@type":"ListItem","position":2,"name":"Rationale and design of a prospective study on the first integrated PET\/dual-energy CT system for staging and image-based radiation therapy planning of lung cancer"}]},{"@type":"WebSite","@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/#website","url":"https:\/\/journals.myesr.org\/eur-radiol-exp\/","name":"European Radiology Experimental","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/journals.myesr.org\/eur-radiol-exp\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Person","@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/#\/schema\/person\/9e0037141ecf4639286bd117d53c7f8f","name":"devsk","image":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/journals.myesr.org\/eur-radiol-exp\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/4ee8d4f6e30c151a9fa73266563f66052dc70da05f90a1df876c0269843f9ecb?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/4ee8d4f6e30c151a9fa73266563f66052dc70da05f90a1df876c0269843f9ecb?s=96&d=mm&r=g","caption":"devsk"},"sameAs":["https:\/\/journals.myesr.org"],"url":"https:\/\/journals.myesr.org\/eur-radiol-exp\/author\/devsk\/"}]}},"_links":{"self":[{"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/posts\/143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/comments?post=143"}],"version-history":[{"count":1,"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/posts\/143\/revisions"}],"predecessor-version":[{"id":145,"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/posts\/143\/revisions\/145"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/media\/27"}],"wp:attachment":[{"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/media?parent=143"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/categories?post=143"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/journals.myesr.org\/eur-radiol-exp\/wp-json\/wp\/v2\/tags?post=143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}